hrp0089p2-p171 | Fat, Metabolism and Obesity P2 | ESPE2018

Gender and Pubertal Tendencies of Plasma leptin and Dopamine Levels Depending on TaqIA DRD2 Gene Polymorphism in the Different Pediatric Obesity Classes

Viazava Liudmila , Solntsava Anzhalika , Aksionava Alena , Dashkevich Alena

Study aim was to evaluate the contribution of DRD2 gene TaqIA polymorphism, plasma leptin and dopamine concentrations to obesity development in children with different adiposity classes, depending on gender and pubertal stage.Materials and methods: 223 children aged from 11 to 17.9 years were involved in the retrospective one-stage analysis, 179 of them were randomly genotyped in the TaqIA of DRD2 gene and blood dopamine (BD) concentrations were detected...